A consortium of health-sector players based in France’s Auvergne-Rhône-Alpes region is advancing the development of an organ-on-a-chip 3D skin model designed to test skin sensitization. The project aims to deliver a fully innervated and immunocompetent tissue construct, integrating sensory nerve cells and immune functionality to more accurately mimic human skin responses. This approach addresses a critical need in cosmetic, chemical, and pharmaceutical testing by providing a reliable in vitro alternative to animal testing for allergic contact dermatitis and other sensitization endpoints. The initiative underscores the region’s growing expertise in bioengineering and organ-on-chip technologies, positioning the consortium to contribute to next-generation toxicology platforms.

Un consortium d’acteurs de la santé, implantés en Auvergne Rhône-Alpes, se lance dans la course au développement d’un modèle de peau 3D innervé et immunocompétent.